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加拿大Medicago ?
公司是基于植物技術(shù)的組合式人體疫苗研發(fā)先鋒。面對流行性傳染病和季節(jié)性傳染病疫苗供求的挑戰(zhàn)，公司成功研制出自有知識產(chǎn)權(quán)的瞬變表達系統(tǒng)，該系統(tǒng)使用來自于非轉(zhuǎn)基因植物葉片中的抗原。 公司位于加拿大魁北克市，擁有1300平方米的領(lǐng)軍設(shè)施，包括高科技溫室及下游研發(fā)設(shè)備。 公司提供多種優(yōu)于傳統(tǒng)蛋基技術(shù)及細胞培植技術(shù)的強勢：速度（3個月內(nèi)即產(chǎn)出數(shù)百萬劑），單支劑量的生產(chǎn)成本，以及極低的投資。 目前的產(chǎn)品包括疫苗抗體組合：HA和 NA流感抗體，以及大面積傳染性疾病疫苗。

?Medicago is developing highly effective and affordable vaccines based on two proprietary technologies: its plant-based Proficia? manufacturing technology and its Virus-Like Particles (VLPs). Proficia? is a robust vaccine and antibody production system based on protein expression in plant leaves. This technology has the potential to offer speed and cost advantages over traditional egg-based and cell production systems. It can deliver a vaccine for testing in less than a month after the identification and reception of genetic sequences from a pandemic strain. Medicago’s VLPs resemble a virus, allowing them to be recognized readily by the immune system however they lack the core genetic material, making them non-infectious and unable to replicate. The Company is currently using tobacco leaves to produce pandemic and seasonal influenza VLP vaccines.
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